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Alex (Lam) Tsoi, PhD

Assistant Professor
Medicine, Public Health

Dr. Tsoi completed his PhD in biomedical science at the Medical University of South Carolina, supervised by Dr. W Jim Zheng. His PhD work focused on developing data integration approaches to enhance prioritization and interpretation of high throughput experimental results. Dr. Tsoi then worked as a research fellow in the Center for Statistical Genetics from the Department of Biostatistics at the University of Michigan. He has been working with Dr. Goncalo Abecasis and Dr. James T Elder on a variety of genetics and genomics projects for psoriasis. He joined the Department of Dermatology, Department of Computational Medicine & Bioinformatics, and the Department of Biostatistics at the University of Michigan between 2015-2016 as a faculty. Dr. Tsoi has strong interests in investigating the pathology and genetic architecture of complex cutaneous disorders using systems biology approaches. Working with Drs. James T. Elder and Johann E Gudjonsson, Dr. Tsoi’s research aims to develop analysis pipelines and computational approaches to provide biological inferences from genetics and genomics data. His work in genetic association studies revealed over 30 novel psoriasis susceptibility regions, and highlighted different disease pathways. He also led the analysis and developed computational pipeline to study psoriasis transcriptomes, and his work uncovered over 1,000 novel transcripts in skin.



University Affiliation(s)


Research Area(s)

Genetics / Genomics / other OMICS


  • Principal investigator of: Integrative and trans-ethnic study of psoriasis heterogeneity
  • Consultant on: Genetically-engineered mouse modeling of Merkel cell carcinoma: cross-species credentialing studies
  • Co-investigator of: JMJD3 Regulates Abdominal Aortic Aneurysm Expansion
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