Chad Brummett
Bert N LaDu Professor of Anesthesiology Research; Professor of Anesthesiology
Anesthesiology
Medicine
MD, Indiana University
Chad Brummett is the Director of the Division of Pain Research and the Director of Clinical Research in the Department of Anesthesiology. His interests include predictors of chronic post-surgical pain as well as failure to derive benefit from interventions and surgeries done primarily for pain. He also leads an institution-wide initiative to create a biorepository for research of genetic factors associated with the development of disease and response to treatment. In addition, Dr. Brummett was the first to describe the use of peripheral perineural dexmedetomidine, and his early research focused on the efficacy, safety, and mechanisms of dexmedetomidine added to local anesthetics for peripheral nerve blocks. He has since translated that work to humans.
Projects:
MGI, Precision Opioid Prescribing
University Affiliation(s)
IHPI | Injury Center
Community and Professional Affiliation(s)
M-OPEN
Research Area(s)
Clinical research | Drug Monitoring | Genetics / Genomics / other OMICS
Publications
- Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development
- Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve
- Opioid prescribing patterns, patient use, and postoperative pain after hysterectomy for benign indications
Grants
- Consultant on: Predicting Myocardial Injury after Noncardiac Surgery through Integration of Genetics and Electronic Health Records
- Co-investigator of: New machine learning methods for modeling opioid use among surgical patients
- Consultant on: The Impact of Personalized Provider Feedback on Opioid Prescribing after Cesarean Delivery: A Randomized Controlled Trial