Dave Bridges
Assistant Professor
Nutritional Sciences
Public Health
PhD in Biochemistry
My team wants to understand the molecular networks that lie at the intersection between metabolism and health. I did my undergraduate and doctoral training in Biochemistry at the University of Calgary, followed by a fellowship with Dr. Alan Saltiel at the University of Michigan. During that time we used several model systems including yeast, flies and mice to elucidate a variety of novel aspects of metabolic regulation. My team studies the molecular, cellular and physiological changes associated with obesity. We are particularly interested in the role of the central nutrient responsive protein kinase mTORC1, how it is altered in weight gain and how its activation affects obesity related co-morbidities. With a better understanding of the molecular mechanisms underlying obesity, we hope to better prevent and treat obesity in the future.
Projects:
Genetics of Obesity, Individual Responses to Low Carbohydrate High Fat Diets
University Affiliation(s)
MDRC | MLEEaD | MNORC | Rogel Cancer Center
Research Area(s)
Disease Modeling | Genetics / Genomics / other OMICS
Grants
- Principal investigator of: Enhancement of Glucocorticoid Signaling by Obesity
- Mentor of: Effects of Manipulation of the Feeding Window During Gestation on Maternal and Child Health
- Principal investigator of: Cellular resolution of breast milk biosynthesis and the impact of diet